Enalapril

In Aotearoa New Zealand enalapril is available as tablets (5 mg, 10 mg and 20 mg). 

• The dose of enalapril will be different for different people depending on your condition.
• Your doctor will usually start you on a low dose so it doesn't make you feel dizzy. Your dose will be increased slowly over a few weeks depending on how you respond. This allows your body to get used to the medicine and reduces side effects.
• Always take your enalapril exactly as your doctor has told you. The pharmacy label on your medicine will tell you how much to take, how often to take it and any special instructions.
• Check with your pharmacist if your tablets are different to what you expect.

My dose

You can use the table below to keep track of dose changes when you start taking enalapril.

• Timing: Enalapril is usually taken once a day but some people may take their doses two times a day. Take your enalapril dose at the same time each day. You can take enalapril with or without food.
• Limit or avoid alcohol while you are taking enalapril. Alcohol can increase your chance of side effects such as dizziness and light-headedness.
• Missed dose: If you forget to take your dose, take it as soon as you remember. But if it is nearly time for your next dose, just take the next dose at the right time. Do not take double the dose.

Enalapril is not suitable if you are pregnant or planning a pregnancy. It is also not suitable if you have had a severe allergic reaction to an ACE inhibitor in the past, eg, swelling of your lips, eyes or tongue (called angioedema). Read more about who cannot take ACE inhibitors. If you are already taking diuretics (water pills), your doctor will monitor you very closely when you first start taking enalapril.

Here are some things to know when you're taking enalapril. Other things may be important as well, so ask your healthcare provider what you should know about.

Monitoring

Your doctor will arrange for you to have blood tests and blood pressure checks before you start taking enalapril and during your treatment, especially when you first start taking it. This is to check how it is working and to check your kidneys and potassium levels.

Have a sick day plan

If you have diarrhoea (runny poo) or are vomiting (being sick) from a stomach bug, or are dehydrated from another illness, it’s important to let your healthcare provider know, as they may advise you to stop taking your enalapril for a few days, or decrease the dose and start again when you feel better. 

Be careful when taking some pain relief medicines

ACE inhibitors can be used to protect your kidneys from damage if you have diabetes. However, if you are taking enalapril and diuretics (water pills), the combination of these with NSAIDs (anti-inflammatory pain relief medicines) can be very harmful to your kidneys. It can cause acute kidney injury. This combination is called the ‘dangerous trio’ or ‘triple whammy’. You have a higher risk of harm to your kidneys if you are also an older adult (over 65 years) or are dehydrated. 

If you are taking an ACE inhibitor with a diuretic, do not use NSAIDs for pain relief. Ask your doctor or pharmacist for a safer option. Read more about NSAIDs and protecting your kidneys.

Are you pregnant or planning a pregnancy?

Tell your doctor if you become pregnant or are planning a pregnancy while you are taking enalapril.

Like all medicines enalapril can cause side effects, although not everyone gets them. Often side effects improve as your body gets used to the new medicine.